Résultat de recherche

05 - Décembre - 2020

Gut microbiota-derived metabolites as central regulators in metabolic disorders (Équipe Seksik - Sokol) Allison Agus, Karine Clement, Harry Sokol

Gut. 2020 Metabolic disorders represent a growing worldwide health challenge due to their dramatically increasing prevalence. The gut microbiota is a crucial actor that can interact with...

29 - Septembre - 2020

Impact of N-Acyl-Homoserine Lactones, Quorum Sensing Molecules, on Gut Immunity (Équipe Seksik - Sokol) Garance Coquant, Jean-Pierre Grill, Philippe Seksik

Front Immunol. 2020;11:1827 Among numerous molecules found in the gut ecosystem, quorum sensing (QS) molecules represent an overlooked part that warrants highlighting. QS relies on the...

30 - Août - 2020

Linking Strain Engraftment in Fecal Microbiota Transplantation With Maintenance of Remission in Crohn's Disease (Équipe Seksik - Sokol) Lingjia Kong, Jason Lloyd-Price, Tommi Vatanen, Philippe Seksik, Laurent Beaugerie, Tabassome Simon, Hera Vlamakis, Harry Sokol, Xavier J Ramnik

Gastroenterology. 2020;159(6):2193-202 e5 BACKGROUND & AIMS : Crohn's disease (CD) is a chronic gastrointestinal disease resulting from the dysfunctional interplay between genetic...

20 - Septembre - 2020

Jejunum: The understudied meeting place of dietary lipids and the microbiota (Équipe Seksik - Sokol ) Ingrid Lema, Joao Ricardo Araujo, Nathalie Rolhion, Sylvie Demignot

Biochimie. 2020;178:124-36 Although the jejunum is the main intestinal compartment responsible for lipid digestion and absorption, most of the studies assessing the impact of dietary lipids...

19 - Septembre - 2020

The Gut Microbiota at the Service of Immunometabolism (Équipe Seksik - Sokol) Chloé Michaudel, Harry Sokol

Cell Metab. 2020;32(4):514-23 The gut microbiota is implicated in immune system functions. Regulation of the metabolic processes occurring in immune cells is crucial for the maintenance of...

02 - Décembre - 2020

Tryptophan Metabolism as a Pharmacological Target (Équipe Seksik - Sokol) Morgane Modoux Nathalie Rolhion Sridhar Mani Harry Sokol

Trends Pharmacol Sci. 2020 L-Tryptophan is an essential amino acid required for protein synthesis. It undergoes an extensive and complex metabolism along several pathways, resulting in many...

17 - Décembre - 2020

Anti-Inflammatory Effects of Analogues of N-Acyl Homoserine Lactones on Eukaryotic Cells (Équipe Seksik - Sokol) Agathe Peyrottes, Garance Coquant, Loic Brot, Dominique Rainteau, Philippe Seksik, Jean-Pierre Grill, Jean-Maurice Mallet

Int J Mol Sci. 2020;21(24) BACKGROUND : Since acyl-homoserine lactone (AHL) profiling has been described in the gut of healthy subjects and patients with inflammatory bowel disease (IBD),...

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