Gut Microbes. 2021;13(1):1-19
The current pandemic of coronavirus disease (COVID) 2019 constitutes a global public health issue. Regarding the emerging importance of the gut-lung axis in...
Nat Rev Gastroenterol Hepatol. 2021
Faecal microbiota transplantation (FMT) is a promising therapy for chronic diseases associated with gut microbiota alterations. FMT cures 90% of...
Sci Rep. 2020;10(1):8852
The cholinergic system plays a major anti-inflammatory role in many diseases through acetylcholine (Ach) release after vagus nerve stimulation. Osteoarthritis (OA)...
Arthritis Rheumatol. 2020
OBJECTIVE : The non-neuronal cholinergic system represents non-neuronal cells that have the biochemical machinery to synthetize de novo and/or respond to...
Joint Bone Spine. 2020
OBJECTIVES : To establish recommendations for pharmacological treatment of knee osteoarthritis specific to France.
METHODS : On behalf of the French Society of...
Osteoarthritis Cartilage. 2020;28(10):1373-84
OBJECTIVE : TGFbeta is a key player in cartilage homeostasis and OA pathology. However, few data are available on the role of TGFbeta...
Osteoarthritis Cartilage. 2020;28(5):646-57
OBJECTIVE : The innate immune system plays a central role in osteoarthritis (OA). We identified 14-3-3epsilon as a novel mediator that guides...
Lancet. 2020;395(10235):1481
As of April 27, 2020, more than two million people worldwide have been diagnosed with coronavirus disease 2019 (COVID-19), with Europe being one of the current...
BioRxiv
The major challenge of the COVID-19 health crisis is to identify the factors of susceptibility to SARS-Cov2 in order to adapt the recommendations to the populations and to reduce...
Front Immunol. 2020;11:1229
COVID-19 is caused by the Severe Acute Respiratory Syndrome (SARS) coronavirus (Cov)-2, an enveloped virus with a positive-polarity, single-stranded RNA genome....
Nat Rev Immunol. 2020;20(9):515-6
The high neutrophil to lymphocyte ratio observed in critically ill patients with COVID-19 is associated with excessive levels of reactive oxygen species...
Dis Model Mech. 2020;13(4)
Normothermic perfusion provides a means to rescue steatotic liver grafts, including by pharmacological defatting. In this study, we tested the potential of new...
J Hepatol. 2019 [Epub ahead of print]
Background & Aims : In non-alcoholic fatty liver disease (NAFLD), hepatocytes can undergo necroptosis: a regulated form of necrotic cell death...
ACS Nano. 2020;14(5):5738-53
Physical oncology recognizes tissue stiffness mediated by activation of cancer-associated fibroblasts (CAF) and extracellular matrix remodeling as an active...
Cancers (Basel). 2020;12(5)
Through the last decade, cold atmospheric plasma (CAP) has emerged as an innovative therapeutic option for cancer treatment. Recently, we have set up a...
Mucosal Immunol. 2020
Humans share a core intestinal microbiome and yet human microbiome differs by genes, species, enterotypes (ecology), and gene count (microbial diversity). Achievement...
