Osteoarthritis Cartilage. 2020;28(10):1373-84
OBJECTIVE : TGFbeta is a key player in cartilage homeostasis and OA pathology. However, few data are available on the role of TGFbeta...
Osteoarthritis Cartilage. 2020;28(5):646-57
OBJECTIVE : The innate immune system plays a central role in osteoarthritis (OA). We identified 14-3-3epsilon as a novel mediator that guides...
(Équipe Corvol)
Dans la mucoviscidose (CF pour Cystic Fibrosis ), Pseudomonas aeruginosa ( P. aeruginosa ) colonise les voies respiratoires, conduisant à une inflammation...
Lancet. 2020;395(10235):1481
As of April 27, 2020, more than two million people worldwide have been diagnosed with coronavirus disease 2019 (COVID-19), with Europe being one of the current...
BioRxiv
The major challenge of the COVID-19 health crisis is to identify the factors of susceptibility to SARS-Cov2 in order to adapt the recommendations to the populations and to reduce...
Front Immunol. 2020;11:1229
COVID-19 is caused by the Severe Acute Respiratory Syndrome (SARS) coronavirus (Cov)-2, an enveloped virus with a positive-polarity, single-stranded RNA genome....
(Équipe Corvol)
La mucoviscidose (ou cystic fibrosis, CF) est une maladie caractérisée par une inflammation pulmonaire chronique. Elle contribue à la...
Nat Rev Immunol. 2020;20(9):515-6
The high neutrophil to lymphocyte ratio observed in critically ill patients with COVID-19 is associated with excessive levels of reactive oxygen species...
Dis Model Mech. 2020;13(4)
Normothermic perfusion provides a means to rescue steatotic liver grafts, including by pharmacological defatting. In this study, we tested the potential of new...
J Hepatol. 2019 [Epub ahead of print]
Background & Aims : In non-alcoholic fatty liver disease (NAFLD), hepatocytes can undergo necroptosis: a regulated form of necrotic cell death...
ACS Nano. 2020;14(5):5738-53
Physical oncology recognizes tissue stiffness mediated by activation of cancer-associated fibroblasts (CAF) and extracellular matrix remodeling as an active...
Cancers (Basel). 2020;12(5)
Through the last decade, cold atmospheric plasma (CAP) has emerged as an innovative therapeutic option for cancer treatment. Recently, we have set up a...