Dernières publications

Publication de diverses études scientifiques

04 - Août - 2021

EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence (Équipe Housset / Équipe Fève)

Elife. 2021;10. Epoxide hydrolases (EHs) regulate cellular homeostasis through hydrolysis of epoxides to less-reactive diols. The first discovered EH was EPHX1, also known as mEH. EH...

08 - Juillet - 2021

Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal gammadelta T cells (Équipe Seksik - Sokol / Équipe Netchine)

Cell Rep. 2021;36(1):109332 Gut interleukin-17A (IL-17)-producing gammadelta T cells are tissue-resident cells that are involved in both host defense and regulation of intestinal...

29 - Avril - 2021

Recipient factors in faecal microbiota transplantation: one stool does not fit all (Équipe Seksik - Sokol)

Nat Rev Gastroenterol Hepatol. 2021 Faecal microbiota transplantation (FMT) is a promising therapy for chronic diseases associated with gut microbiota alterations. FMT cures 90% of...

10 - Mars - 2021

SARS-CoV-2 infection in nonhuman primates alters the composition and functional activity of the gut microbiota (Équipe Seksik - Sokol)

Gut Microbes. 2021;13(1):1-19 The current pandemic of coronavirus disease (COVID) 2019 constitutes a global public health issue. Regarding the emerging importance of the gut-lung axis in...

12 - Février - 2021

Tryptophan metabolites get the gut moving (Équipe Seksik - Sokol )

Cell Host Microbe. 2021;29(2):145-7 How gut microbes can regulate the enteric nervous system and gut-brain communications is a field of intense research. In this issue of Cell Host &...

09 - Février - 2021

Low-phospholipid-associated cholelithiasis syndrome: Prevalence, clinical features, and comorbidities (Équipe Housset )

JHEP Rep. 2021;3(2):100201 Background & Aims : Low-phospholipid-associated cholelithiasis (LPAC) syndrome, a rare genetic form of intrahepatic cholelithiasis in adults, is still poorly...

03 - Février - 2021

Glial cells and adaptive immunity in frontotemporal dementia with tau pathology (Équipe Dorothée)

Brain. 2021 Neuroinflammation is involved in the aetiology of many neurodegenerative disorders including Alzheimer's disease, Parkinson's disease and motor neuron disease. Whether...

09 - Janvier - 2021

Cholangiopathy aggravation is caused by VDR ablation and alleviated by VDR-independent vitamin D signaling in ABCB4 knockout mice (Équipe Housset)

Biochim Biophys Acta Mol Basis Dis. 2021;1867(4):166067 BACKGROUND & AIMS : Cholangiopathies are chronic liver diseases in which damaged cholangiocytes trigger a proinflammatory and...

17 - Décembre - 2020

Anti-Inflammatory Effects of Analogues of N-Acyl Homoserine Lactones on Eukaryotic Cells (Équipe Seksik - Sokol)

Int J Mol Sci. 2020;21(24) BACKGROUND : Since acyl-homoserine lactone (AHL) profiling has been described in the gut of healthy subjects and patients with inflammatory bowel disease (IBD),...

15 - Décembre - 2020

Insights from the genetic characterization of central precocious puberty associated with multiple anomalies (Équipe Netchine)

Hum Reprod. 2021 Jan 25;36(2):506-518 STUDY QUESTION : Is there an (epi)genetic basis in patients with central precocious puberty (CPP) associated with multiple anomalies that unmasks...
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