Dernières publications

Publication de diverses études scientifiques

01 - Juin - 2020

Broad-spectrum antiviral activity of naproxen: from Influenza A to SARS-CoV-2 Coronavirus (Équipe Sabbah)

bioRxiv 2020 There is an urgent need for specific antiviral drugs directed against SARS-CoV-2 both to prevent the most severe forms of COVID-19 and to reduce viral excretion and subsequent...

01 - Juin - 2020

Clearing method for 3-dimensional immunofluorescence of osteoarthritic subchondral human bone reveals peripheral cholinergic nerves (Équipe Berenbaum)

Sci Rep. 2020;10(1):8852 The cholinergic system plays a major anti-inflammatory role in many diseases through acetylcholine (Ach) release after vagus nerve stimulation. Osteoarthritis (OA)...

23 - Mai - 2020

Cold-Atmospheric Plasma Induces Tumor Cell Death in Preclinical In Vivo and In Vitro Models of Human Cholangiocarcinoma (Équipe Housset)

Cancers (Basel). 2020;12(5) Through the last decade, cold atmospheric plasma (CAP) has emerged as an innovative therapeutic option for cancer treatment. Recently, we have set up a...

14 - Mai - 2020

BHRF1, a BCL2 viral homolog, disturbs mitochondrial dynamics and stimulates mitophagy to dampen type I IFN induction (Équipe Sabbah)

Autophagy 17 (2021): 1296-1315 Mitochondria respond to many cellular functions and act as central hubs in innate immunity against viruses. This response is notably due to their role in the...

04 - Mai - 2020

AhR activation defends gut barrier integrity against damage occurring in obesity (Équipe Seksik - Sokol)

Mol Metab. 2020;39:101007 OBJECTIVE : Obesity is characterized by systemic and low-grade tissue inflammation. In the intestine, alteration of the intestinal barrier and accumulation of...

01 - Mai - 2020

Atypical presentation of COVID-19 in young infants (Équipe Corvol)

Lancet. 2020;395(10235):1481 As of April 27, 2020, more than two million people worldwide have been diagnosed with coronavirus disease 2019 (COVID-19), with Europe being one of the current...

28 - Avril - 2020

Photothermal Depletion of Cancer-Associated Fibroblasts Normalizes Tumor Stiffness in Desmoplastic Cholangiocarcinoma (Équipe Housset)

ACS Nano. 2020;14(5):5738-53 Physical oncology recognizes tissue stiffness mediated by activation of cancer-associated fibroblasts (CAF) and extracellular matrix remodeling as an active...

17 - Mars - 2020

Activation of innate immunity by 14-3-3 epsilon, a new potential alarmin in osteoarthritis (Équipe Berenbaum)

Osteoarthritis Cartilage. 2020;28(5):646-57 OBJECTIVE : The innate immune system plays a central role in osteoarthritis (OA). We identified 14-3-3epsilon as a novel mediator that guides...

15 - Mars - 2020

Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease (Équipe Housset)

J Hepatol. 2019 [Epub ahead of print] Background & Aims : In non-alcoholic fatty liver disease (NAFLD), hepatocytes can undergo necroptosis: a regulated form of necrotic cell death...

26 - Février - 2020

Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis (Équipe Housset)

Dis Model Mech. 2020;13(4) Normothermic perfusion provides a means to rescue steatotic liver grafts, including by pharmacological defatting. In this study, we tested the potential of new...
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