Dernières publications

Publication de diverses études scientifiques

10 - Juillet - 2020

Arsenic trioxide induces regulatory functions of plasmacytoid dendritic cells through interferon- alpha inhibition (Équipe Mohty )

Acta Pharm Sin B. 2020;10(6):1061-72 Arsenic trioxide (As2O3) is recently found to have therapeutic potential in systemic sclerosis (SSc), a life-threatening multi-system fibrosing...

09 - Juillet - 2020

The Role of the Non-neuronal Cholinergic System in Inflammation and Degradation Processes in Osteoarthritis (Équipe Berenbaum)

Arthritis Rheumatol. 2020 OBJECTIVE : The non-neuronal cholinergic system represents non-neuronal cells that have the biochemical machinery to synthetize de novo and/or respond to...

03 - Juillet - 2020

The Spatial Heterogeneity of the Gut Limits Predation and Fosters Coexistence of Bacteria and Bacteriophages (Équipe Seksik - Sokol)

Cell Host Microbe. 2020;28(3):390-401 e5 The ecological dynamics underlying the coexistence between antagonistic populations of bacteria and their viruses, bacteriophages (phages), in the...

24 - Juin - 2020

Innate Immune Signaling and Proteolytic Pathways in the Resolution or Exacerbation of SARS-CoV-2 in Covid-19: Key Therapeutic Targets? (Équipe Corvol)

Front Immunol. 2020;11:1229 COVID-19 is caused by the Severe Acute Respiratory Syndrome (SARS) coronavirus (Cov)-2, an enveloped virus with a positive-polarity, single-stranded RNA genome....

04 - Juin - 2020

Plasmacytoid dendritic cell biology and its role in immune-mediated diseases (Équipe Mohty)

Clin Transl Immunology. 2020;9(5):e1139 Plasmacytoid dendritic cells (pDCs) are a unique subset of dendritic cells specialised in secreting high levels of type I interferons. pDCs play a...

01 - Juin - 2020

Broad-spectrum antiviral activity of naproxen: from Influenza A to SARS-CoV-2 Coronavirus (Équipe Sabbah)

bioRxiv 2020 There is an urgent need for specific antiviral drugs directed against SARS-CoV-2 both to prevent the most severe forms of COVID-19 and to reduce viral excretion and subsequent...

01 - Juin - 2020

Clearing method for 3-dimensional immunofluorescence of osteoarthritic subchondral human bone reveals peripheral cholinergic nerves (Équipe Berenbaum)

Sci Rep. 2020;10(1):8852 The cholinergic system plays a major anti-inflammatory role in many diseases through acetylcholine (Ach) release after vagus nerve stimulation. Osteoarthritis (OA)...

23 - Mai - 2020

Cold-Atmospheric Plasma Induces Tumor Cell Death in Preclinical In Vivo and In Vitro Models of Human Cholangiocarcinoma (Équipe Housset)

Cancers (Basel). 2020;12(5) Through the last decade, cold atmospheric plasma (CAP) has emerged as an innovative therapeutic option for cancer treatment. Recently, we have set up a...

14 - Mai - 2020

BHRF1, a BCL2 viral homolog, disturbs mitochondrial dynamics and stimulates mitophagy to dampen type I IFN induction (Équipe Sabbah)

Autophagy 17 (2021): 1296-1315 Mitochondria respond to many cellular functions and act as central hubs in innate immunity against viruses. This response is notably due to their role in the...

04 - Mai - 2020

AhR activation defends gut barrier integrity against damage occurring in obesity (Équipe Seksik - Sokol)

Mol Metab. 2020;39:101007 OBJECTIVE : Obesity is characterized by systemic and low-grade tissue inflammation. In the intestine, alteration of the intestinal barrier and accumulation of...
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