Dernières publications

Publication de diverses études scientifiques

26 - Février - 2022

Factors Predisposing the Response to Lumacaftor/Ivacaftor in People with Cystic Fibrosis (Équipe Corvol)

J Pers Med 2022; 12 Lumacaftor/ivacaftor (LUMA-IVA) therapy is prescribed to people with cystic fibrosis (pwCF) homozygous for the Phe508del-CFTR variant to restore CFTR protein function....

26 - Février - 2022

Impact of the Ileal Microbiota on Surgical Site Infections in Crohn's Disease: A Nationwide Prospective Cohort (Équipe Seksik - Sokol)

J Crohns Colitis 2022 BACKGROUND : Surgery is performed in 50-70% of Crohn's disease (CD) patients, and its main risk is surgical site infection (SSI). The microbiota has been extensively...

10 - Février - 2022

MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression (Équipe Gautheron/Housset)

Cells 2022 Vol. 11 Issue 4 ABCB4, is an adenosine triphosphate-binding cassette (ABC) transporter localized at the canalicular membrane of hepatocytes, where it mediates phosphatidylcholine...

28 - Janvier - 2022

Liraglutide, a glucagon-like peptide 1 receptor agonist, exerts analgesic, anti-inflammatory and anti-degradative actions in osteoarthritis (Équipe Berenbaum)

Sci Rep 2022 Vol. 12 Issue 1 Pages 1567 Osteoarthritis (OA) is a common disabling disease worldwide, with no effective and safe disease-modifying drugs (DMOAD) in the market. However,...

07 - Décembre - 2021

Flagellin From Pseudomonas aeruginosa Modulates SARS-CoV-2 Infectivity in Cystic Fibrosis Airway Epithelial Cells by Increasing TMPRSS2 Expression (Équipe Corvol)

Front Immunol 2021 Vol. 12 Pages 714027 In the coronavirus disease 2019 (COVID-19) health crisis, one major challenge is to identify the susceptibility factors of severe acute respiratory...

12 - Octobre - 2021

Risk factors for Pseudomonas aeruginosa airway infection and lung function decline in children with cystic fibrosis (Équipe Corvol)

J Cyst Fibros. 2021 Background Cystic fibrosis (CF) lung disease is characterised by recurrent Pseudomonas aeruginosa (Pa) infections, leading to structural lung damage and decreased...

25 - Septembre - 2021

Circulating cytokines present in multiple myeloma patients inhibit the osteoblastic differentiation of adipose stem cells (Équipe Sabbah)

Leukemia (2021) Myeloma is characterized by bone lesions, which are related to both an increased osteoclast activity and a defect in the differentiation of medullary mesenchymal stem cells...

16 - Septembre - 2021

Peripheral and central immune system crosstalk in Alzheimer disease - a research prospectus (Équipe Dorothée)

Nat Rev Neurol. 2021 Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a considerable body of evidence indicates that pathological alterations in...

01 - Septembre - 2021

TFH cells in systemic sclerosis (Équipe Mohty)

cells in systemic sclerosis. J Transl Med 19 (2021): 375 Systemic sclerosis is an autoimmune disease characterized by excessive dermal fibrosis with progression to internal organs, vascular...

12 - Août - 2021

Weak immunogenicity of SARS-CoV-2 vaccine in patients with hematologic malignancies (Équipe Mohty)

Blood Cancer J 11 (2021): 142 This study evaluated the safety and immunogenicity of BNT162b2 vaccine in patients with hematological malignancies. Antibodies blocking spike binding to...
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