Dernières publications CRSA, Centre de Recherche de l’hôpital Saint-Antoine

11 - Juin - 2024

ADH1B, the adipocyte-enriched alcohol dehydrogenase, plays an essential, cell-autonomous role in human adipogenesis

Proc Natl Acad Sci U S A. 2024 Jun 11;121(24):e2319301121. Alcohol dehydrogenase 1B (ADH1B) is a primate-specific enzyme which, uniquely among the ADH class 1 family, is highly expressed...

06 - Juin - 2024

The path to next-generation disease-modifying immunomodulatory combination therapies in Alzheimer's disease (Équipe Dorothée)

Nat Aging. 2024 Jun;4(6):761-770 The cautious optimism following recent anti-amyloid therapeutic trials for Alzheimer's disease (AD) provides a glimmer of hope after years of...

31 - Mai - 2024

The procoagulant signature of cancer cells drives brin network formation in tumor microenvironment and impacts its quality. Implications in cancer cell migration and the resistance to anticancer agents (Équipe Sabbah)

Thromb Res. 2024 Jun;238:172-183. doi: 10.1016/j.thromres.2024.04.015. Epub 2024 Apr 17. Fibrin Clot Shields from Cancer Cells: A Barrier to Treatment and Schaffold for Migration Our...

05 - Avril - 2024

Identification of Cellular Protein Targets of a Half-Sandwich Iridium(III) Complex Reveals Its Dual Mechanism of Action via Both Electrophilic and Oxidative Stresses (Équipe Prunier)

J Med Chem. 2024 Apr 25;67(8):6189-6206 Identification of intracellular targets of anticancer drug candidates provides key information on their mechanism of action. Exploiting the...

29 - Mars - 2024

Features of cryptococcosis among 652 HIV-seronegative individuals in France: a cross-sectional observational study (2005-2020) (Équipe Seksik/Sokol)

Clin Microbiol Infect. 2024 Mar 29:S1198-743X(24)00162-9 OBJECTIVES : We aimed to describe features and outcomes of cryptococcosis among HIV-seronegative individuals in a large...

07 - Mars - 2024

Molecular epidemiology of Candida africana isolates collected from vagina swabs in French Guiana (Équipe Corvol/Guillot)

Med Mycol. 2024 Mar 7;62(3):myae016 Previous molecular studies have shown that Candida africana corresponds to the clade 13 of Candia albicans. It has been mostly involved in...

07 - Mars - 2024

[Antimicrobial peptides: A new alternative for the treatment of aspergillosis] (Équipe Corvol/Guillot)

Rev Mal Respir. 2024 Apr;41(4):283-288 Aspergillus fumigatus is the predominant fungal species causing pulmonary aspergillosis. The present-day anti-aspergillosis arsenal is limited,...

14 - Novembre - 2023

Adipocyte glucocorticoid receptor activation with high glucocorticoid doses impairs healthy adipose tissue expansion by repressing angiogenesis (Équipe Fève)

Diabetes. 2023 Nov 14:db230165. doi: 10.2337/db23-0165 In Human, glucocorticoids (GC) are commonly prescribed because of their anti-inflammatory and immunosuppressive properties. However,...

20 - Juin - 2023

The developmental basis for scaling of mammalian tooth size

Proc Natl Acad Sci U S A 2023 Jun 20;120(25) When evolution leads to differences in body size, organs generally scale along. A well-known example of the tight relationship between...

01 - Juin - 2023

Prediction of response to immune checkpoint blockade in patients with metastatic colorectal cancer with microsatellite instability (Équipe Duval)

Ann Oncol. 2023 Aug;34(8):703-713 BACKGROUND : Mismatch repair-deficient (dMMR) tumors displaying microsatellite instability (MSI) represent a paradigm for the success of immune...

Dernières publications

Publication de diverses études scientifiques