Dernières publications

Publication de diverses études scientifiques

01 - Juin - 2023

Prediction of response to immune checkpoint blockade in patients with metastatic colorectal cancer with microsatellite instability (Équipe Duval)

Ann Oncol. 2023 Aug;34(8):703-713 BACKGROUND : Mismatch repair-deficient (dMMR) tumors displaying microsatellite instability (MSI) represent a paradigm for the success of immune...

14 - Avril - 2023

Targeting the gut microbiota in inflammatory bowel diseases: where are we? (Équipe Seksik/Sokol)

Curr Opin Microbiol. 2023 Apr 14;74:102319 The gut microbiota is now recognized to be a key driver of mucosal inflammation in inflammatory bowel disease (IBD). Robust functional and...

07 - Avril - 2023

The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia (Équipe Prunier)

BMC Biol 2023 Vol. 21 Issue 1 Pages 73 BACKGROUND : E3 ubiquitin ligases play critical roles in regulating cellular signaling pathways by inducing ubiquitylation of key components....

08 - Janvier - 2023

Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases (Équipe Gautheron/Housset)

Int J Mol Sci. 2023 Jan 8;24(2):1236 ABCB4 (ATP-binding cassette subfamily B member 4) is a hepatocanalicular floppase involved in biliary phosphatidylcholine (PC) secretion. Variations in...

29 - Décembre - 2022

Maintenance of methylation profile in imprinting control regions in human induced pluripotent stem cells (Équipe Netchine)

Clin Epigenetics 2022; 14: 190. BACKGROUND : Parental imprinting is an epigenetic mechanism that leads to monoallelic expression of a subset of genes depending on their parental origin....

22 - Décembre - 2022

Fibroblast growth factor-2 bound to specific dermal fibroblast-derived extracellular vesicles is protected from degradation (Équipe Prunier)

Sci Rep 2022 Vol. 12 Issue 1 Pages 22131 Fibroblast growth factor-2 (FGF2) has multiple roles in cutaneous wound healing but its natural low stability prevents the development of its use in...

06 - Décembre - 2022

Interference with Lipoprotein Maturation Sensitizes Methicillin-Resistant Staphylococcus aureus to Human Group IIA-Secreted Phospholipase A2 and Daptomycin (Équipe Corvol)

J Innate Immun. 2022 Dec 6:1-18 Methicillin-resistant Staphylococcus aureus (MRSA) has been classified as a high priority pathogen by the World Health Organization underlining the high...

06 - Décembre - 2022

Impact of IBD-Associated Dysbiosis on Bacterial Quorum Sensing Mediated by Acyl-Homoserine Lactone in Human Gut Microbiota (Équipe Seksik/Sokol)

Int J Mol Sci. 2022 Dec 6;23(23):15404 Intestinal dysbiosis is a key feature in the pathogenesis of inflammatory bowel disease (IBD). Acyl-homoserine lactones (AHL) are bacterial...

01 - Décembre - 2022

Diversity of the nucleic acid forms of circulating HBV in chronically infected patients and its impact on viral cycle (Équipe Gautheron/Housset)

Hepatol Int 2022 Vol. 16 Issue 6 Pages 1259-1272 BACKGROUND : Besides the prototypical hepatitis B virus (HBV) infectious particle, which contains a full-length double-stranded DNA...
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