Dernières publications

Publication de diverses études scientifiques

11 - Janvier - 2019

Impairment of glyoxalase-1, an advanced glycation end-product detoxifying enzyme, induced by inflammation in age-related osteoarthritis (Équipe Berenbaum)

Arthritis Res Ther. 2019;21(1):18 Background : Accumulation of advanced glycation end-products (AGEs) is involved in age-related osteoarthritis (OA). Glyoxalase (Glo)-1 is the main enzyme...

10 - Janvier - 2019

Predictive Value of Cellular Accumulation of Hydrophobic Bile Acids As a Marker of Cholestatic Drug Potential (Équipe Seksik/Sokol)

Toxicol Sci. 2019;168(2):474-85 Drug-induced cholestasis is mostly intrahepatic and characterized by alterations of bile canaliculi dynamics and morphology as well as accumulation of bile...

01 - Janvier - 2019

Adaptive beta-Cell Neogenesis in the Adult Mouse in Response to Glucocorticoid-Induced Insulin Resistance (Équipe Fève)

Diabetes. 2019;68(1):95-108 Both type 1 and type 2 diabetes are characterized by deficient insulin secretion and decreased beta-cell mass. Thus, regenerative strategies to increase...

01 - Janvier - 2019

Glucocorticoid-induced insulin resistance is related to macrophage visceral adipose tissue infiltration (Équipe Fève)

J Steroid Biochem Mol Biol. 2019;185:150-62 Insulin resistance is frequently present in patients with glucocorticoid (GC) excess (Cushing's syndrome) or treated with high doses of GCs....

22 - Décembre - 2018

The Phenotypic Approach to Osteoarthritis: A Look at Metabolic Syndrome-Associated Osteoarthritis (Équipe Berenbaum)

Joint Bone Spine. 2018 Metabolic syndrome-associated osteoarthritis (Met-OA) is a clinical phenotype defined by the role of obesity and metabolic syndrome as risk factors and by chronic...

19 - Décembre - 2018

LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis (Équipe Housset)

Aliment Pharmacol Ther. 2019;49(3):308-20 Background : No blood test has been shown to be effective in the prediction of primary liver cancer in patients without cirrhosis. AIM: To...

01 - Décembre - 2018

Diet-Induced Dysbiosis and Genetic Background Synergize With Cystic Fibrosis Transmembrane Conductance Regulator Deficiency to Promote Cholangiopathy in Mice (Équipes Housset - Seksik/Sokol)

Hepatol Commun. 2018;2(12):1533-49 The most typical expression of cystic fibrosis (CF)-related liver disease is a cholangiopathy that can progress to cirrhosis. We aimed to determine the...

06 - Novembre - 2018

Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome (Équipe Seksik/Sokol)

Cell Metab. 2018;28(5):737-49 e4 The extent to which microbiota alterations define or influence the outcome of metabolic diseases is still unclear, but the byproducts of microbiota...

01 - Novembre - 2018

Bile acid homeostasis and intestinal dysbiosis in alcoholic hepatitis (Équipe Seksik/Sokol)

Aliment Pharmacol Ther. 2018;48(9):961-74 Background : Intestinal microbiota plays an important role in bile acid homeostasis. Aim : To study the structure of the intestinal microbiota...

22 - Octobre - 2018

Mixed signals from the cell's antennae: primary cilia in cancer (Équipe Seksik/Sokol)

EMBO Rep. 2018;19(11) Primary cilia (PC) are antenna-like organelles that protrude from most mammalian cells. They are essential for the regulation of several signaling pathways such as...
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