Lancet. 2020;395(10235):1481
As of April 27, 2020, more than two million people worldwide have been diagnosed with coronavirus disease 2019 (COVID-19), with Europe being one of the current...
BioRxiv
The major challenge of the COVID-19 health crisis is to identify the factors of susceptibility to SARS-Cov2 in order to adapt the recommendations to the populations and to reduce...
(Équipe Housset)
La fibrose hépatique est la conséquence de toutes les maladies chroniques du foie et se caractérise par un dépôt excessif de matrice...
Front Immunol. 2020;11:1229
COVID-19 is caused by the Severe Acute Respiratory Syndrome (SARS) coronavirus (Cov)-2, an enveloped virus with a positive-polarity, single-stranded RNA genome....
Nat Rev Immunol. 2020;20(9):515-6
The high neutrophil to lymphocyte ratio observed in critically ill patients with COVID-19 is associated with excessive levels of reactive oxygen species...
Dis Model Mech. 2020;13(4)
Normothermic perfusion provides a means to rescue steatotic liver grafts, including by pharmacological defatting. In this study, we tested the potential of new...
(Équipe Fève)
Leptin deficiency, which correlates with the decreased amount of body fat, was shown to contribute to lipodystrophy-associated metabolic complications. Recombinant...
J Hepatol. 2019 [Epub ahead of print]
Background & Aims : In non-alcoholic fatty liver disease (NAFLD), hepatocytes can undergo necroptosis: a regulated form of necrotic cell death...
ACS Nano. 2020;14(5):5738-53
Physical oncology recognizes tissue stiffness mediated by activation of cancer-associated fibroblasts (CAF) and extracellular matrix remodeling as an active...
Cancers (Basel). 2020;12(5)
Through the last decade, cold atmospheric plasma (CAP) has emerged as an innovative therapeutic option for cancer treatment. Recently, we have set up a...
Mucosal Immunol. 2020
Humans share a core intestinal microbiome and yet human microbiome differs by genes, species, enterotypes (ecology), and gene count (microbial diversity). Achievement...
Acta Pharm Sin B. 2020;10(6):1061-72
Arsenic trioxide (As2O3) is recently found to have therapeutic potential in systemic sclerosis (SSc), a life-threatening multi-system fibrosing...
Clin Transl Immunology. 2020;9(5):e1139
Plasmacytoid dendritic cells (pDCs) are a unique subset of dendritic cells specialised in secreting high levels of type I interferons. pDCs play a...