(Équipe Housset)
Contexte : Le carcinome hépatocellulaire (CHC) est le cancer primitif du foie le plus fréquent. Il survient dans 75% à 80% des cas sur cirrhose....
Mol Neurodegener 2022 Vol. 17 Issue 1 Pages 19
BACKGROUND : The implication of gut microbiota in the control of brain functions in health and disease is a novel, currently emerging...
(Équipe Mohty)
La sclérodermie systémique (SSc) est une maladie auto-immune, caractérisée par une atteinte microvasculaire oblitérante, de la fibrose...
Cell Mol Life Sci 2022; 79: 332
Heat shock proteins (HSPs) play oncogenic roles in human tumours. We reported a somatic inactivating mutation of HSP110 (HSP110DE9) in mismatch...
Hepatology 2022
BACKGROUND AND AIMS : Receptor-interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the...
Cells 2022 Vol. 11 Issue 4
ABCB4, is an adenosine triphosphate-binding cassette (ABC) transporter localized at the canalicular membrane of hepatocytes, where it mediates phosphatidylcholine...
J Hepatol 2022 Vol. 77 Issue 3 Pages 761-806
Management of primary or secondary sclerosing cholangitis is challenging. These Clinical Practice Guidelines have been developed to provide...
Journal of Physics D: Applied Physics, Volume 55, Number 45
For the past 12 years, cold plasmas (i.e. weakly ionized gas) have been positioned as a breakthrough technology for treating...
Transl Oncol 2022 Vol. 26 Pages 101531
Correct actin cytoskeleton organization is vital in the liver organ homeostasis and disease control. Rearrangements of the actin cytoskeleton may play...
(Équipe Corvol)
Dans la mucoviscidose (CF pour Cystic Fibrosis ), Pseudomonas aeruginosa ( P. aeruginosa ) colonise les voies respiratoires, conduisant à une inflammation...
BMC Med. 2022 Mar 28;20(1):95
BACKGROUND : Thymidine phosphorylase (TP), encoded by the TYMP gene, is a cytosolic enzyme essential for the nucleotide salvage pathway. TP catalyzes the...
Hepatology 2022
BACKGROUND & AIMS : In liver fibrosis, myofibroblasts derive from hepatic stellate cells (HSCs) and as yet undefined mesenchymal cells. We aimed to identify portal...