Dernières publications CRSA, Centre de Recherche de l’hôpital Saint-Antoine

21 - Octobre - 2025

Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4+ T cells to confer protection against intestinal inflammations

Nat Metab. 2025 Oct 21 ABSTRACT: The gut microbiota and its metabolites critically regulate immune cell phenotype, function and energy metabolism. We screened a collection of gut...

10 - Octobre - 2025

Antifungal activity of ETD151 against azole-susceptible and -resistant Aspergillus fumigatus clinical isolates (Équipe Corvol & Guillot)

Aspergillus fumigatus is an opportunistic pathogen responsible for a wide spectrum of severe diseases, depending on the host's immune status. Current therapeutic options against this...

09 - Octobre - 2025

Immunometabolic reprogramming of macrophages by gut microbiota-derived cadaverine controls colon inflammation

Cell Host Microbe. 2025 Sep 30:S1931-3128(25)00375-0. ABSTRACT: Cadaverine is a polyamine produced by the gut microbiota with links to health and disease, notably inflammatory bowel...

08 - Octobre - 2025

Gut microbiota alterations are linked to COVID-19 severity in North African and European populations

NPJ Biofilms Microbiomes. 2025 juin 13;11(1):106 ABSTRACT: Although COVID-19 primarily affects the respiratory system, many patients experience gastrointestinal symptoms, suggesting a...

06 - Octobre - 2025

Adipocyte-specific Mlkl knockout mitigates obesity-induced metabolic dysfunction by enhancing mitochondrial functions

Cell Death Dis. 2025 Oct 6;16(1):683 Obesity is a global epidemic characterized by chronic low-grade inflammation and metabolic dysfunction, with adipose tissue playing a pivotal...

03 - Octobre - 2025

Prognostic value of liver stiffness measurement vs. biochemical response in primary biliary cholangitis

J Hepatol. 2026 Feb;84(2):275-283 Background & aims: Both liver stiffness measurement (LSM) and biochemical response have prognostic significance in patients with primary...

29 - Septembre - 2025

Pre-emptive TIPS should be considered in high-risk patients with both acute variceal bleeding and severe alcohol-related hepatitis

JHEP Rep. 2025 Sep 29;7(12):101611. Background & aims: Severe alcohol-related hepatitis (AH) and acute variceal bleeding (AVB) may occur simultaneously. The impact of a...

24 - Septembre - 2025

The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity (Équipe Corvol/Guillot)

Genes Immun. 2025 Sep 24 Innate immune memory, also called trained immunity, refers to the ability of innate immune cells to gain memory characteristics after transient stimulation, resulting...

15 - Septembre - 2025

Adaptation à des cellules bêta dévoilées: Le rôle des myokines chez les souris résistantes à l'insuline (Équipe Fève)

Cell Rep. 2025 Sep 13;44(9):116283 Les cellules bêta pancréatiques peuvent adapter leur masse et leur fonction pour maintenir une glycémie normale en cas de...

23 - Juillet - 2025

Les progéniteurs lymphoïdes générés ex vivo peuvent donner naissance à la fois à des cellules T et à des cellules lymphoïdes innées (Plateforme de Cytométrie)

Immunole avant. 2025 Juillet 23:16:1617707 Introduction : We previously established a feeder-free cell therapy platform for the ex vivo generation of lymphoid-primed progenitors using...

Dernières publications

Publication de diverses études scientifiques