Clin Gastroenterol Hepatol. 2019
Background & Aims : Primary sclerosing cholangitis (PSC) has a variable, often progressive course. Magnetic resonance cholangiography (MRC) is used in...
Sci Rep. 2019;9(1):6653
Adenosine triphosphate binding cassette transporter, subfamily B member 4 (ABCB4) is the transporter of phosphatidylcholine at the canalicular membrane of...
Sci. Adv. 2019; 5 : eaau9425
Clinical and molecular overlap in imprinting disorders
Imprinting disorders (ID) often affect growth in humans, leading to diseases with overlapping...
Nat Rev Endocrinol. 2019;15(5):299-311
Overgrowth syndromes are a heterogeneous group of rare disorders characterized by generalized or segmental excessive growth commonly associated with...
Sleep Med. 2019;on line
Objective ; Imprinting disorders (ID), such as Prader−Willi syndrome (PWS), are associated with sleep-disordered breathing (SDB). No data are available for...
Front Endocrinol (Lausanne). 2019;10:263
We report an original association of complex genetic defects in a patient carrying both an 11p paternal duplication, resulting in the double...
J Med Genet. 2019
Background : The type 1 insulin-like growth factor receptor (IGF1R) is a keystone of fetal growth regulation by mediating the effects of IGF-I and IGF-II. Recently, a...
PLoS Genet. 2019;15(3):e1008018
Several bacteria in the gut microbiota have been shown to be associated with inflammatory bowel disease (IBD), and dozens of IBD genetic variants have been...
Toxicol Sci. 2019;168(2):474-85
Drug-induced cholestasis is mostly intrahepatic and characterized by alterations of bile canaliculi dynamics and morphology as well as accumulation of bile...
Biochim Biophys Acta Mol Cell Biol Lipids. 2020;1865(2):158530
The mechanisms leading to the low-grade inflammation observed during obesity are not fully understood. Seeking the initiating...
Microbiome. 2019;7(1):111
Background : Normal mammalian development and homeostasis are dependent upon the gut microbiota. Antibiotics, essential for the treatment and prophylaxis of...
Nutr Rev. 2019;77(3):129-43
The plasticity of a material corresponds to its capacity to change its feature under the effect of an external action. Intestinal plasticity could be defined as...
Gut. 2019
Objective : We explored the hypothesis that TGR5, the bile acid (BA) G-protein-coupled receptor highly expressed in biliary epithelial cells, protects the liver against BA...
Nat Rev Gastroenterol Hepatol. 2019;16(6):331-45
The gut microbiota is a dense and diverse ecosystem that is involved in many physiological functions as well as in disease pathogenesis. It...