Nat Rev Rheumatol 17 (2021): 533-549
Osteoarthritis (OA) is a whole-joint disease characterized by subchondral bone perfusion abnormalities and neovascular invasion into the synovium and...
Sci Rep 2021 Vol. 11 Issue 1 Pages 11886
The cholinergic system has been proposed as a potential regulator of COVID-19-induced hypercytokinemia. We investigated whole-blood expression of...
Joint Bone Spine 88 (2021): 105149
The vagus nerve is the main nerve of the parasympathetic autonomic nervous system. Beyond its vegetative functions, the vagus nerve possesses...
Osteoarthritis Cartilage 29 (2021): 257-268
OBJECTIVES : We hypothesize that chondrocytes from the deepest articular cartilage layer are pivotal in maintaining cartilage integrity and that...
J Cyst Fibros. 2021
Background Cystic fibrosis (CF) lung disease is characterised by recurrent Pseudomonas aeruginosa (Pa) infections, leading to structural lung damage and decreased...
Front Immunol 2021 Vol. 12 Pages 714027
In the coronavirus disease 2019 (COVID-19) health crisis, one major challenge is to identify the susceptibility factors of severe acute respiratory...
Curr Opin Rheumatol 33 (2021): 84-93
PURPOSE OF REVIEW : Epidemiologic studies reveal that the link between obesity and osteoarthritis cannot be uniquely explained by overweight-associated...
Nat Rev Neurol. 2021
Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a considerable body of evidence indicates that pathological alterations in...
Brain. 2021
Neuroinflammation is involved in the aetiology of many neurodegenerative disorders including Alzheimer's disease, Parkinson's disease and motor neuron disease. Whether...
Gastroenterology 161 (2021): 814-826 e7
BACKGROUND & AIMS : Next-generation sequencing (NGS) was recently approved by the United States Food and Drug Administration to detect...
JHEP Rep. 2021;3(2):100201
Background & Aims : Low-phospholipid-associated cholelithiasis (LPAC) syndrome, a rare genetic form of intrahepatic cholelithiasis in adults, is still poorly...
Elife. 2021;10.
Epoxide hydrolases (EHs) regulate cellular homeostasis through hydrolysis of epoxides to less-reactive diols. The first discovered EH was EPHX1, also known as mEH. EH...
cells in systemic sclerosis. J Transl Med 19 (2021): 375
Systemic sclerosis is an autoimmune disease characterized by excessive dermal fibrosis with progression to internal organs, vascular...
Blood Cancer J 11 (2021): 142
This study evaluated the safety and immunogenicity of BNT162b2 vaccine in patients with hematological malignancies. Antibodies blocking spike binding to...
Mucosal Immunol 14 (2021): 1127-1132
Patients receiving allogeneic hematopoietic cell transplantation (alloHCT) were previously shown to display a bacterial gut dysbiosis; however, limited...
