Dernières publications CRSA, Centre de Recherche de l’hôpital Saint-Antoine

01 - Novembre - 2022

Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis (Équipe Gautheron/Housset)

Hepatology 2022 BACKGROUND & AIMS : In liver fibrosis, myofibroblasts derive from hepatic stellate cells (HSCs) and as yet undefined mesenchymal cells. We aimed to identify portal...

21 - Octobre - 2022

The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes (Équipe Gautheron/Housset / Fève)

iScience, Volume 25, ISSUE 10, 105166, October 21, 2022 Receptor-interacting protein kinase-3 (RIPK3) and mixed lineage kinase domain- like (MLKL) proteins are key regulators of...

21 - Octobre - 2022

Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases (Équipe Seksik/Sokol)

Gut. 2023 Jul;72(7):1296-1307 OBJECTIVE : The extent to which tryptophan (Trp) metabolism alterations explain or influence the outcome of inflammatory bowel diseases (IBDs) is still...

27 - Septembre - 2022

CARD9 in neutrophils protects from colitis and controls mitochondrial metabolism and cell survival (Équipe XXXX)

Gut. 2022 OBJECTIVES : Inflammatory bowel disease (IBD) results from a combination of genetic predisposition, dysbiosis of the gut microbiota and environmental factors, leading to...

16 - Septembre - 2022

Cold plasma endoscopy applied to biliary ducts: feasibility risk assessment on human-like and porcine models for the treatment of cholangiocarcinoma (Équipe Gautheron-Housset)

Journal of Physics D: Applied Physics, Volume 55, Number 45 For the past 12 years, cold plasmas (i.e. weakly ionized gas) have been positioned as a breakthrough technology for treating...

13 - Septembre - 2022

Unraveling the actin cytoskeleton in the malignant transformation of cholangiocyte biology (Équipe Gautheron/Housset)

Transl Oncol 2022 Vol. 26 Pages 101531 Correct actin cytoskeleton organization is vital in the liver organ homeostasis and disease control. Rearrangements of the actin cytoskeleton may play...

01 - Septembre - 2022

Genetic alterations shaping tumor response to anti-EGFR therapies (Équipe Gautheron/Housset)

Drug Resist Updat 2022 Vol. 64 Pages 100863 The Epidermal Growth Factor Receptor (EGFR) has been targeted through the development of selective tyrosine kinase inhibitors (TKIs) and...

01 - Septembre - 2022

EASL Clinical Practice Guidelines on sclerosing cholangitis (Équipe Gautheron/Housset)

J Hepatol 2022 Vol. 77 Issue 3 Pages 761-806 Management of primary or secondary sclerosing cholangitis is challenging. These Clinical Practice Guidelines have been developed to provide...

27 - Août - 2022

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease (Équipe Gautheron/Housset / Fève)

Hepatology 2022 BACKGROUND AND AIMS : Receptor-interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the...

15 - Juin - 2022

Pollutants: a candidate as a new risk factor for osteoarthritis-results from a systematic literature review (Équipe Berenbaum)

RMD Open 2022; 8 BACKGROUND : Considering non-classical environmental risk factors for osteoarthritis (OA), a systematic literature review (SLR) was performed to summarise existing...

Dernières publications

Publication de diverses études scientifiques