Dernières publications CRSA, Centre de Recherche de l’hôpital Saint-Antoine

22 - Novembre - 2025

ABCB4 disease-causing variants S242R, S346I, T437I and T1077M significantly impair its function and display differential sensitivity to potentiators

Sci Rep. 2025 Nov 22. The hepato-canalicular adenosine triphosphate (ATP)-binding cassette transporter ABCB4/MDR3 is responsible of the secretion of phosphatidylcholine (PC) into...

07 - Novembre - 2025

Saccharomyces boulardii CNCM I-745 mitigates antibiotic-induced gut microbiome functional alterations independently of the host

Gut Microbes. 2025 Dec 31;17(1):2575924 ABSTRACT: The probiotic Saccharomyces boulardii CNCM I-745 (Sb) is widely prescribed to alleviate antibiotic-induced diarrhea, yet its mode of...

06 - Novembre - 2025

MALADIES FIBRO-INFLAMMATOIRES D'ORIGINE METABOLIQUES ET BILIAIRES DU FOIE

https://www.crsa.fr/equipe-jeremie-gautheron.html

28 - Octobre - 2025

Targeting the gut microbiome in inflammatory bowel disease: from concept to clinical reality

Intest Res. 2025 Oct;23(4):396-404 ABSTRACT: The gut microbiota, a complex community of trillions of microorganisms inhabiting the human gastrointestinal tract, has emerged as a...

21 - Octobre - 2025

Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4+ T cells to confer protection against intestinal inflammations

Nat Metab. 2025 Oct 21 ABSTRACT: The gut microbiota and its metabolites critically regulate immune cell phenotype, function and energy metabolism. We screened a collection of gut...

10 - Octobre - 2025

Antifungal activity of ETD151 against azole-susceptible and -resistant Aspergillus fumigatus clinical isolates (Équipe Corvol & Guillot)

Aspergillus fumigatus is an opportunistic pathogen responsible for a wide spectrum of severe diseases, depending on the host's immune status. Current therapeutic options against this...

09 - Octobre - 2025

Immunometabolic reprogramming of macrophages by gut microbiota-derived cadaverine controls colon inflammation

Cell Host Microbe. 2025 Sep 30:S1931-3128(25)00375-0. ABSTRACT: Cadaverine is a polyamine produced by the gut microbiota with links to health and disease, notably inflammatory bowel...

08 - Octobre - 2025

Gut microbiota alterations are linked to COVID-19 severity in North African and European populations

NPJ Biofilms Microbiomes. 2025 juin 13;11(1):106 ABSTRACT: Although COVID-19 primarily affects the respiratory system, many patients experience gastrointestinal symptoms, suggesting a...

06 - Octobre - 2025

Adipocyte-specific Mlkl knockout mitigates obesity-induced metabolic dysfunction by enhancing mitochondrial functions

Cell Death Dis. 2025 Oct 6;16(1):683 Obesity is a global epidemic characterized by chronic low-grade inflammation and metabolic dysfunction, with adipose tissue playing a pivotal...

24 - Septembre - 2025

The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity (Équipe Corvol/Guillot)

Genes Immun. 2025 Sep 24 Innate immune memory, also called trained immunity, refers to the ability of innate immune cells to gain memory characteristics after transient stimulation, resulting...

Dernières publications

Publication de diverses études scientifiques