Nat Rev Endocrinol. 2018;14(4):229-49
Beckwith–Wiedemann syndrome (BWS), a human genomic imprinting disorder, is characterized by phenotypic variability that might include overgrowth,...
Med Genet. 2018;55(3):205-13
Background : The 11p15 region contains two clusters of imprinted genes. Opposite genetic and epigenetic anomalies of this region result in two distinct growth...
Gut. 2017;66(12):2160-9
Objective : HCV is intimately linked with the liver lipid metabolism, devoted to the efflux of triacylglycerols stored in lipid droplets (LDs) in the form of...
Science. 2017;358(6364):803-6
Cell division and differentiation depend on massive and rapid organelle remodeling. The mitotic oscillator, centered on the cyclin-dependent kinase...
J Clin Endocrinol Metab. 2017;102(11):3970-8
Context : Anti-Mullerian hormone (AMH) and AMH type II receptor (AMHR2) are overexpressed in granulosa cells (GCs) from women with polycystic...
Best Pract Res Clin Rheumatol. 2017;31(5):661-75
Joint homeostasis is affected by local and systemic processes. Catecholaminergic and cholinergic fibers innervate the synovium, trabecular...
Proc Natl Acad Sci U S A. 2017;114(36):9731-6
When food resources are scarce, endothermic animals can lower core body temperature (Tb). This phenomenon is believed to be part of an adaptive...
Cancer Genomics Proteomics. 2017;14(5):329-39
Background/Aim : The aim of this study was to assess the incidence of MSI in a large series of human hepatocellular carcinomas (HCC) with...
Genet Med. 2018;20(2):250-8
Purpose : Fetal growth is a complex process involving maternal, placental and fetal factors. The etiology of fetal growth retardation remains unknown in many...
F1000Res. 2017;6:724
Nucleoside triphosphate (NTP)s, like ATP (adenosine 5'-triphosphate) and GTP (guanosine 5'-triphosphate), have long been considered sufficiently concentrated and...
Ann Endocrinol (Paris). 2017;78(2):92-5
Abstract
Organism development is controlled by both genetic programs and the environment to insure a reproductive success as adults. Linear...
Biochim Biophys Acta Mol Basis Dis. 2017;1863(7):1699-708
Nuclear receptors (NR), the largest family of transcription factors, control many physiological and pathological processes. To gain...
PLoS One. 2017;12(6):e0179913
Induced pluripotent stem cells hold great potential to produce unlimited amount of differentiated cells as cellular source for regenerative medicine but also...
Diabetes. 2017;66(6):1470-8
Activation of thermogenic beige adipocytes has recently emerged as a promising therapeutic target in obesity and diabetes. Relevant human models for beige...
Gut. 2017;66(6):1039-48
Objective : The bacterial intestinal microbiota plays major roles in human physiology and IBDs. Although some data suggest a role of the fungal microbiota in IBD...
Sci Rep. 2017;7(1):1749
WISP1 (Wnt1-inducible signaling pathway protein-1, also known as CCN4) is a member of the CCN family able to mediate cell growth, transformation and survival in a...
J Med Genet. 2017;54(6):413-6
Background : Type-2 familial partial lipodystrophy (FPLD2) is a rare autosomal dominant lipodystrophic disorder due to mutations in LMNA encoding lamin A/C, a...
Ann Rheum Dis. 2017;76(6):1142-8
Objectives : Compared with subcutaneous adipose tissue (SCAT), infrapatellar fat pad (IFP), the main knee intra-articular adipose tissue (IAAT), has an...
Curr Opin Rheumatol. 2017;29(2):214-22
Purpose of review : Interest in the metabolic syndrome-associated osteoarthritis phenotype is increasing. Here, we summarize recently published...
Hepatology. 2017;65(2):560-70
ABCB4 (MDR3) is an adenosine triphosphate (ATP)-binding cassette (ABC) transporter expressed at the canalicular membrane of hepatocytes, where it mediates...
Mol Metab. 2017;6(1):61-72
Objective : Intestinal glucose absorption is orchestrated by specialized glucose transporters such as SGLT1 and GLUT2. However, the role of GLUT2 in the...
PLoS One. 2017;12(1):e0170083
Nutrition during the perinatal period programs body growth. Growth hormone (GH) secretion from the pituitary regulates body growth and is controlled by Growth...
FASEB J. 2017;31(4):1531-46
NME1 (nonmetastatic expressed 1) gene, which encodes nucleoside diphosphate kinase (NDPK) A [also known as nonmetastatic clone 23 (NM23)-H1 in humans and NM23-M1...
Nat Rev Rheumatol. 2016;12(11):669-83
Alarmins (also known as danger signals) are endogenous molecules that are released to the extracellular milieu after infection or tissue damage....
