Liver Int. 2019
Background and aims : The ABCC2 gene is implicated in Dubin-Johnson syndrome (DJS), a rare autosomal recessive liver disorder. The primary aim of this study was to determine...
Microbiome. 2019;7(1):111
Background : Normal mammalian development and homeostasis are dependent upon the gut microbiota. Antibiotics, essential for the treatment and prophylaxis of...
Sleep Med. 2019;on line
Objective ; Imprinting disorders (ID), such as Prader−Willi syndrome (PWS), are associated with sleep-disordered breathing (SDB). No data are available for...
Sci Rep. 2019;9(1):6653
Adenosine triphosphate binding cassette transporter, subfamily B member 4 (ABCB4) is the transporter of phosphatidylcholine at the canalicular membrane of...
Gut. 2019
Objective : Patients with primary sclerosing cholangitis (PSC) were previously shown to display a bacterial gut dysbiosis but fungal microbiota has never been examined in these...
Dev Biol. 2019;448(2):237-46
At the onset of the Ciona intestinalis metamorphosis, the first event is tail regression characterized, by a contraction, an apoptotic wave and Primordial Germ...
Journal of Physics D: Applied Physics. 2019;52(24)
Two atmospheric pressure plasma jet (APPJ) devices—a plasma gun and a plasma Tesla jet—are compared in terms of safety and...
Clin Gastroenterol Hepatol. 2019
Background & Aims : Primary sclerosing cholangitis (PSC) has a variable, often progressive course. Magnetic resonance cholangiography (MRC) is used in...
PLoS Genet. 2019;15(3):e1008018
Several bacteria in the gut microbiota have been shown to be associated with inflammatory bowel disease (IBD), and dozens of IBD genetic variants have been...
Nat Rev Endocrinol. 2019;15(5):299-311
Overgrowth syndromes are a heterogeneous group of rare disorders characterized by generalized or segmental excessive growth commonly associated with...
Nat Rev Gastroenterol Hepatol. 2019;16(6):331-45
The gut microbiota is a dense and diverse ecosystem that is involved in many physiological functions as well as in disease pathogenesis. It...
Nutr Rev. 2019;77(3):129-43
The plasticity of a material corresponds to its capacity to change its feature under the effect of an external action. Intestinal plasticity could be defined as...
Sci. Adv. 2019; 5 : eaau9425
Clinical and molecular overlap in imprinting disorders
Imprinting disorders (ID) often affect growth in humans, leading to diseases with overlapping...
Genetics in Medicine 2019
Purpose : The SERPINA1 Z allele is associated with cystic fibrosis (CF)-related liver disease (CFLD), a common manifestation in patients with CF. We estimated...
Gut. 2019
Objective : We explored the hypothesis that TGR5, the bile acid (BA) G-protein-coupled receptor highly expressed in biliary epithelial cells, protects the liver against BA...
Diabetes. 2019;68(2):305-17
Widely used for their anti-inflammatory and immunosuppressive properties, glucocorticoids are nonetheless responsible for the development of diabetes and...
Arthritis Res Ther. 2019;21(1):18
Background : Accumulation of advanced glycation end-products (AGEs) is involved in age-related osteoarthritis (OA). Glyoxalase (Glo)-1 is the main enzyme...
Toxicol Sci. 2019;168(2):474-85
Drug-induced cholestasis is mostly intrahepatic and characterized by alterations of bile canaliculi dynamics and morphology as well as accumulation of bile...
Diabetes. 2019;68(1):95-108
Both type 1 and type 2 diabetes are characterized by deficient insulin secretion and decreased beta-cell mass. Thus, regenerative strategies to increase...
J Steroid Biochem Mol Biol. 2019;185:150-62
Insulin resistance is frequently present in patients with glucocorticoid (GC) excess (Cushing's syndrome) or treated with high doses of GCs....
Joint Bone Spine. 2018
Metabolic syndrome-associated osteoarthritis (Met-OA) is a clinical phenotype defined by the role of obesity and metabolic syndrome as risk factors and by chronic...
Aliment Pharmacol Ther. 2019;49(3):308-20
Background : No blood test has been shown to be effective in the prediction of primary liver cancer in patients without cirrhosis. AIM: To...
Hepatol Commun. 2018;2(12):1533-49
The most typical expression of cystic fibrosis (CF)-related liver disease is a cholangiopathy that can progress to cirrhosis. We aimed to determine the...
Cell Metab. 2018;28(5):737-49 e4
The extent to which microbiota alterations define or influence the outcome of metabolic diseases is still unclear, but the byproducts of microbiota...
Aliment Pharmacol Ther. 2018;48(9):961-74
Background : Intestinal microbiota plays an important role in bile acid homeostasis.
Aim : To study the structure of the intestinal microbiota...
EMBO Rep. 2018;19(11)
Primary cilia (PC) are antenna-like organelles that protrude from most mammalian cells. They are essential for the regulation of several signaling pathways such as...
Biophys Acta Mol Basis Dis. 2018;1864(12):3688-96
Portal myofibroblasts (PMF) form a sub-population of highly proliferative and proangiogenic liver myofibroblasts that derive from portal...
Gut. 2018;67(10):1836-44
Objective : In association with innate and adaptive immunity, the microbiota controls the colonisation resistance against intestinal pathogens. Caspase recruitment...
Nat Rev Rheumatol. 2018;14(11):674-81
The prevalence of osteoarthritis (OA) is rising for reasons that are not fully understood. In this Opinion article, we review the possibility that OA...
