Sci Rep 2022; 12: 9440
In the gut ecosystem, microorganisms regulate group behaviour and interplay with the host via a molecular system called quorum sensing (QS). The QS molecule...
Int J Mol Sci. 2022 Dec 6;23(23):15404
Intestinal dysbiosis is a key feature in the pathogenesis of inflammatory bowel disease (IBD). Acyl-homoserine lactones (AHL) are bacterial...
J Crohns Colitis 2022
BACKGROUND : Surgery is performed in 50-70% of Crohn's disease (CD) patients, and its main risk is surgical site infection (SSI). The microbiota has been extensively...
(Équipe Housset)
La fibrose hépatique est la conséquence de toutes les maladies chroniques du foie et se caractérise par un dépôt excessif de matrice...
Gut Microbes 2022; 14: 2078620
Due to the potential role of the gut microbiota and bile acids in the pathogenesis of both inflammatory bowel disease (IBD) and sporadic colorectal cancer, we...
JCI Insight 2022
Faecalibacterium prausnitzii (F. prausnitzii), a dominant bacterium of the human microbiota, is decreased in patients with inflammatory bowel diseases (IBD) and exhibits...
(Équipe Fève)
Leptin deficiency, which correlates with the decreased amount of body fat, was shown to contribute to lipodystrophy-associated metabolic complications. Recombinant...
Nat Rev Rheumatol 17 (2021): 533-549
Osteoarthritis (OA) is a whole-joint disease characterized by subchondral bone perfusion abnormalities and neovascular invasion into the synovium and...
Sci Rep 2021 Vol. 11 Issue 1 Pages 11886
The cholinergic system has been proposed as a potential regulator of COVID-19-induced hypercytokinemia. We investigated whole-blood expression of...
Joint Bone Spine 88 (2021): 105149
The vagus nerve is the main nerve of the parasympathetic autonomic nervous system. Beyond its vegetative functions, the vagus nerve possesses...
Osteoarthritis Cartilage 29 (2021): 257-268
OBJECTIVES : We hypothesize that chondrocytes from the deepest articular cartilage layer are pivotal in maintaining cartilage integrity and that...
J Cyst Fibros. 2021
Background Cystic fibrosis (CF) lung disease is characterised by recurrent Pseudomonas aeruginosa (Pa) infections, leading to structural lung damage and decreased...
Front Immunol 2021 Vol. 12 Pages 714027
In the coronavirus disease 2019 (COVID-19) health crisis, one major challenge is to identify the susceptibility factors of severe acute respiratory...
Curr Opin Rheumatol 33 (2021): 84-93
PURPOSE OF REVIEW : Epidemiologic studies reveal that the link between obesity and osteoarthritis cannot be uniquely explained by overweight-associated...
Nat Rev Neurol. 2021
Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a considerable body of evidence indicates that pathological alterations in...