Dernières publications CRSA, Centre de Recherche de l’hôpital Saint-Antoine

02 - Juin - 2022

Consequences of the Hsp110DE9 mutation in tumorigenesis and the 5-fluorouracil-based chemotherapy response in Msh2-deficient mice (Équipe Duval)

Cell Mol Life Sci 2022; 79: 332 Heat shock proteins (HSPs) play oncogenic roles in human tumours. We reported a somatic inactivating mutation of HSP110 (HSP110DE9) in mismatch...

01 - Juin - 2022

Fecal microbiota and bile acids in IBD patients undergoing screening for colorectal cancer (Équipe Seksik/Sokol)

Gut Microbes 2022; 14: 2078620 Due to the potential role of the gut microbiota and bile acids in the pathogenesis of both inflammatory bowel disease (IBD) and sporadic colorectal cancer, we...

28 - Mai - 2022

Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes (Équipe Gautheron/Housset / Fève)

BMC Med. 2022 Mar 28;20(1):95 BACKGROUND : Thymidine phosphorylase (TP), encoded by the TYMP gene, is a cytosolic enzyme essential for the nucleotide salvage pathway. TP catalyzes the...

18 - Mai - 2022

(99m)Tc-NTP 15-5 is a companion radiotracer for assessing joint functional response to sprifermin (rhFGF-18) in a murine osteoarthritis model (Équipe Berenbaum)

Sci Rep 2022; 12: 8146 With the emergence of disease modifying osteoarthritis drugs (DMOAD), imaging methods to quantitatively demonstrate their efficacy and to monitor osteoarthritis...

11 - Mai - 2022

Human CD4+/CD8alpha+ regulatory T cells induced by Faecalibacterium prausnitzii protect against intestinal inflammation (Équipe Seksik-Sokol)

JCI Insight 2022 Faecalibacterium prausnitzii (F. prausnitzii), a dominant bacterium of the human microbiota, is decreased in patients with inflammatory bowel diseases (IBD) and exhibits...

29 - Avril - 2022

Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis (Équipe Berenbaum)

Front Immunol 2022; 13: 842538 Introduction : Osteoarthritis (OA) is a whole-joint disease characterized by a low-grade inflammation that is involved in both cartilage degradation and...

02 - Avril - 2022

Dental pulp stem cells as a promising model to study imprinting diseases (Équipe Netchine)

PInt J Oral Sci 2022; 14: 19 arental imprinting is an epigenetic process leading to monoallelic expression of certain genes depending on their parental origin. Imprinting diseases are...

15 - Mars - 2022

Targeting the GLP-1/GLP-1R axis to treat osteoarthritis: A new opportunity? (Équipe Berenbaum)

J Orthop Translat 2022; 32: 121-129 Osteoarthritis (OA) is a degenerative joint disease affecting millions of people worldwide. In OA, chondrocytes, synovial cells and other joint cells...

14 - Mars - 2022

WISP2/CCN5 Suppresses Vasculogenic Mimicry through Inhibition of YAP/TAZ Signaling in Breast Cancer Cells (Équipe Sabbah)

Cancers (Basel) 2022; 14 Vasculogenic mimicry (VM) formed by aggressive tumor cells to create vascular networks connected with the endothelial cells, plays an important role in breast...

09 - Mars - 2022

SLC6A14 Impacts Cystic Fibrosis Lung Disease Severity via mTOR and Epithelial Repair Modulation (Équipe Corvol)

Front. Mol. Biosci. Cystic fibrosis (CF), due to pathogenic variants in CFTR gene, is associated with chronic infection/inflammation responsible for airway epithelium alteration and lung...

Dernières publications

Publication de diverses études scientifiques