Sci Rep 2022 Vol. 12 Issue 1 Pages 1567
Osteoarthritis (OA) is a common disabling disease worldwide, with no effective and safe disease-modifying drugs (DMOAD) in the market. However,...
J Orthop Translat 2022; 32: 121-129
Osteoarthritis (OA) is a degenerative joint disease affecting millions of people worldwide. In OA, chondrocytes, synovial cells and other joint cells...
(Équipe Housset)
Contexte : Le carcinome hépatocellulaire (CHC) est le cancer primitif du foie le plus fréquent. Il survient dans 75% à 80% des cas sur cirrhose....
Int J Mol Sci 2022; 23
Osteoarthritis (OA) is a whole joint disease characterized by an important remodeling of the osteochondral junction. It includes cartilage mineralization due to...
(Équipe Mohty)
La sclérodermie systémique (SSc) est une maladie auto-immune, caractérisée par une atteinte microvasculaire oblitérante, de la fibrose...
J Fungi (Basel). 2022 Nov 30;8(12):1268
Bronchial epithelial cells (BEC) play a crucial role in innate immunity against inhaled fungi. Indeed, in response to microorganisms, BEC synthesize...
J Innate Immun. 2022 Dec 6:1-18
Methicillin-resistant Staphylococcus aureus (MRSA) has been classified as a high priority pathogen by the World Health Organization underlining the high...
Front. Mol. Biosci.
Cystic fibrosis (CF), due to pathogenic variants in CFTR gene, is associated with chronic infection/inflammation responsible for airway epithelium alteration and lung...
J Pers Med 2022; 12
Lumacaftor/ivacaftor (LUMA-IVA) therapy is prescribed to people with cystic fibrosis (pwCF) homozygous for the Phe508del-CFTR variant to restore CFTR protein function....
Mol Neurodegener 2022 Vol. 17 Issue 1 Pages 19
BACKGROUND : The implication of gut microbiota in the control of brain functions in health and disease is a novel, currently emerging...
Cell Mol Life Sci 2022; 79: 332
Heat shock proteins (HSPs) play oncogenic roles in human tumours. We reported a somatic inactivating mutation of HSP110 (HSP110DE9) in mismatch...
Hepatology 2022
BACKGROUND AND AIMS : Receptor-interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the...
(Équipe Corvol)
Dans la mucoviscidose (CF pour Cystic Fibrosis ), Pseudomonas aeruginosa ( P. aeruginosa ) colonise les voies respiratoires, conduisant à une inflammation...
Cells 2022 Vol. 11 Issue 4
ABCB4, is an adenosine triphosphate-binding cassette (ABC) transporter localized at the canalicular membrane of hepatocytes, where it mediates phosphatidylcholine...
