Nat Rev Neurol. 2021
Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a considerable body of evidence indicates that pathological alterations in...
(Équipe Corvol)
La mucoviscidose (ou cystic fibrosis, CF) est une maladie caractérisée par une inflammation pulmonaire chronique. Elle contribue à la...
Brain. 2021
Neuroinflammation is involved in the aetiology of many neurodegenerative disorders including Alzheimer's disease, Parkinson's disease and motor neuron disease. Whether...
Gastroenterology 161 (2021): 814-826 e7
BACKGROUND & AIMS : Next-generation sequencing (NGS) was recently approved by the United States Food and Drug Administration to detect...
JHEP Rep. 2021;3(2):100201
Background & Aims : Low-phospholipid-associated cholelithiasis (LPAC) syndrome, a rare genetic form of intrahepatic cholelithiasis in adults, is still poorly...
Elife. 2021;10.
Epoxide hydrolases (EHs) regulate cellular homeostasis through hydrolysis of epoxides to less-reactive diols. The first discovered EH was EPHX1, also known as mEH. EH...
(Équipe Housset)
La fibrose hépatique est la conséquence de toutes les maladies chroniques du foie et se caractérise par un dépôt excessif de matrice...
cells in systemic sclerosis. J Transl Med 19 (2021): 375
Systemic sclerosis is an autoimmune disease characterized by excessive dermal fibrosis with progression to internal organs, vascular...
Blood Cancer J 11 (2021): 142
This study evaluated the safety and immunogenicity of BNT162b2 vaccine in patients with hematological malignancies. Antibodies blocking spike binding to...
(Équipe Fève)
Leptin deficiency, which correlates with the decreased amount of body fat, was shown to contribute to lipodystrophy-associated metabolic complications. Recombinant...
Mucosal Immunol 14 (2021): 1127-1132
Patients receiving allogeneic hematopoietic cell transplantation (alloHCT) were previously shown to display a bacterial gut dysbiosis; however, limited...