Dernières publications

Publication de diverses études scientifiques

11 - Décembre - 2020

Introduction to host microbiome symbiosis in health and disease (Équipe Mohty)

Mucosal Immunol. 2020 Humans share a core intestinal microbiome and yet human microbiome differs by genes, species, enterotypes (ecology), and gene count (microbial diversity). Achievement...

11 - Décembre - 2020

The differentiation of prehypertrophic into hypertrophic chondrocytes drives an OA-remodeling program and IL-34 expression (Équipe Berenbaum)

Osteoarthritis Cartilage 29 (2021): 257-268 OBJECTIVES : We hypothesize that chondrocytes from the deepest articular cartilage layer are pivotal in maintaining cartilage integrity and that...

05 - Décembre - 2020

Gut microbiota-derived metabolites as central regulators in metabolic disorders (Équipe Seksik - Sokol)

Gut. 2020 Metabolic disorders represent a growing worldwide health challenge due to their dramatically increasing prevalence. The gut microbiota is a crucial actor that can interact with...

02 - Décembre - 2020

Tryptophan Metabolism as a Pharmacological Target (Équipe Seksik - Sokol)

Trends Pharmacol Sci. 2020 L-Tryptophan is an essential amino acid required for protein synthesis. It undergoes an extensive and complex metabolism along several pathways, resulting in many...

14 - Novembre - 2020

Role of adipose tissues in osteoarthritis (Équipe Berenbaum)

Curr Opin Rheumatol 33 (2021): 84-93 PURPOSE OF REVIEW : Epidemiologic studies reveal that the link between obesity and osteoarthritis cannot be uniquely explained by overweight-associated...

27 - Octobre - 2020

The intestinal quorum sensing 3-oxo-C12:2 Acyl homoserine lactone limits cytokine-induced tight junction disruption (Équipe Seksik - Sokol)

Tissue Barriers. 2020;8(4):1832877 The intestine is home to the largest microbiota community of the human body and strictly regulates its barrier function. Tight junctions (TJ) are major...

23 - Octobre - 2020

Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation (Équipe Seksik - Sokol)

Sci Transl Med. 2020;12(566) Metabolism of tryptophan by the gut microbiota into derivatives that activate the aryl hydrocarbon receptor (AhR) contributes to intestinal homeostasis. Many...

03 - Octobre - 2020

High-dose post-transplant cyclophosphamide impairs gammadelta T-cell reconstitution after haploidentical haematopoietic stem cell transplantation using low-dose antithymocyte globulin and peripheral blood stem cell graft (Équipe Mohty)

Clin Transl Immunology. 2020;9(9):e1171 OBJECTIVES : Haploidentical haematopoietic cell transplantation (Haplo-HCT) using peripheral blood stem cell (PBSC) grafts and post-transplant...

29 - Septembre - 2020

Impact of N-Acyl-Homoserine Lactones, Quorum Sensing Molecules, on Gut Immunity (Équipe Seksik - Sokol)

Front Immunol. 2020;11:1827 Among numerous molecules found in the gut ecosystem, quorum sensing (QS) molecules represent an overlooked part that warrants highlighting. QS relies on the...

23 - Septembre - 2020

Derivation and Validation of a Predictive Score for Disease Worsening in Patients with COVID-19 (Équipe Larsen-Sabbah)

Thromb Haemost. 2020 The prospective observational cohort study COMPASS-COVID-19 aimed to develop a risk assessment model for early identification of hospitalized COVID-19 patients at risk...
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