Dernières publications CRSA, Centre de Recherche de l’hôpital Saint-Antoine

28 - Avril - 2020

Photothermal Depletion of Cancer-Associated Fibroblasts Normalizes Tumor Stiffness in Desmoplastic Cholangiocarcinoma (Équipe Housset)

ACS Nano. 2020;14(5):5738-53 Physical oncology recognizes tissue stiffness mediated by activation of cancer-associated fibroblasts (CAF) and extracellular matrix remodeling as an active...

17 - Mars - 2020

Activation of innate immunity by 14-3-3 epsilon, a new potential alarmin in osteoarthritis (Équipe Berenbaum)

Osteoarthritis Cartilage. 2020;28(5):646-57 OBJECTIVE : The innate immune system plays a central role in osteoarthritis (OA). We identified 14-3-3epsilon as a novel mediator that guides...

15 - Mars - 2020

Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease (Équipe Housset)

J Hepatol. 2019 [Epub ahead of print] Background & Aims : In non-alcoholic fatty liver disease (NAFLD), hepatocytes can undergo necroptosis: a regulated form of necrotic cell death...

26 - Février - 2020

Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis (Équipe Housset)

Dis Model Mech. 2020;13(4) Normothermic perfusion provides a means to rescue steatotic liver grafts, including by pharmacological defatting. In this study, we tested the potential of new...

19 - Décembre - 2019

Breast-Associated Adipocytes Secretome Induce Fatty Acid Uptake and Invasiveness in Breast Cancer Cells via CD36 Independently of Body Mass Index, Menopausal Status and Mammary Density (Équipes Larsen/Sabbah – Fève – Seksik/Sokol)

Cancers (Basel). 2019;11(12) Breast adiposity is correlated with body mass index, menopausal status and mammary density. We here wish to establish how these factors influence the cross-talk...

30 - Novembre - 2019

Contribution of adipocyte precursors in the phenotypic specificity of intra-articular adipose tissues in knee osteoarthritis patients (Équipe Berenbaum)

Arthritis Res Ther. 2019;21(1):252 Background : Intra-articular adipose tissues (IAATs) are involved in osteoarthritis (OA) pathophysiology. We hypothesize that mesenchymal cells residing...

03 - Novembre - 2019

Respiratory Epithelial Cells Can Remember Infection: A Proof of Concept Study (Équipe Corvol)

J Infect Dis. 2019 Human bronchial epithelial cells play a key role in airway immune homeostasis. We hypothesized that these sentinel cells can remember a previous contact with pathogen...

28 - Octobre - 2019

Palmitic acid damages gut epithelium integrity and initiates inflammatory cytokine production (Équipe Seksik/Sokol)

Biochim Biophys Acta Mol Cell Biol Lipids. 2020;1865(2):158530 The mechanisms leading to the low-grade inflammation observed during obesity are not fully understood. Seeking the initiating...

18 - Octobre - 2019

Danger signals and inflammaging in osteoarthritis (Équipe Berenbaum)

Clin Exp Rheumatol. 2019;37 Suppl 120(5):48-56 Osteoarthritis (OA) is the most com- mon age-related chronic and disabling joint disease. Long considered to be a “wear and tear”...

07 - Octobre - 2019

Increasing knowledge in IGF1R defects: lessons from 35 new patients (Équipe Netchine)

J Med Genet. 2019 Background : The type 1 insulin-like growth factor receptor (IGF1R) is a keystone of fetal growth regulation by mediating the effects of IGF-I and IGF-II. Recently, a...

Dernières publications

Publication de diverses études scientifiques