30/05-2022 - Ana-Maria LENNON-DUMENIL : Deciphering the dialog between gut epithelial cells and mononuclear phagocytes

24 - Mai - 2022

LES LUNDIS DE SAINT-ANTOINE

Bâtiment Kourilsky - 13h–14h

Salle des Conférences (Rez de Chaussée),

184 rue du Faubourg Saint-Antoine, Paris

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LUNDI 30 MAI 2022

Deciphering the dialog between gut epithelial cells and mononuclear phagocytes

Ana-Maria LENNON-DUMENIL

INSERM, INSTITUT CURIE

invitée par Equipe de Philippe SEKSIK- Harry SOKOL, (Equipe SEKSIK-SOKOL (philippe.seksik@inserm.fr ; harry.sokol@inserm.fr))

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Within tissues, dendritic cells constitute a complex cell population composed of distinct subsets that can exhibit different activation states and functions. How tissue-specific cues orchestrate dendritic cell diversification remains elusive. In the first part of my seminar, I will discuss unpublished results showing that, by reaching distinct sub-tissular niches within the gut, dendritic cells can exist as immature and mature cells, revealing a novel mechanism of dendritic cell functional diversification. In the second part of my seminar, I will present data highlighting the essential role of macrophages in protecting colonic epithelial cells from being poisoned by fungi toxins. I will discuss the implications of these findings on colon inflammation and cancer.

Afin d'assister à cette conférence vous pourrez vous connecter sur le lien zoom suivant :

Sujet : Lundi de Saint Antoine

30 mai 2022 12:30 PM Paris

Participer à la réunion Zoom

https://us02web.zoom.us/j/84773930363?pwd=RkNSU0t2bXo5enZpVnlaQTJSdGRSQT09

ID de réunion : 847 7393 0363

Code secret : 166346

Hôpital St-Antoine

Bâtiment Kourilsky
34 rue Crozatier
75012 PARIS

Sorbonne Université
27 rue Chaligny
75012 PARIS

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