12/09-2022 - Laurent DEBARBIEUX : Phage therapy, the lengthy path for bacteriophages to reach the patients

08 - Septembre - 2022

LES LUNDIS DE SAINT-ANTOINE

Bâtiment Kourilsky - 13h–14h

Salle des Conférences (Rez de Chaussée),

184 rue du Faubourg Saint-Antoine, Paris

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LUNDI 12 SEPTEMBRE 2022

Phage therapy, the lengthy path for bacteriophages to reach the patients

Charles -Antoine DUTERTRE

Directeur de Recherches

invité par Equipe de Harriet CORVOL, (Equipe CORVOL (harriet.corvol@inserm.fr))

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Antimicrobial resistance is major public health issue because the pipeline of drugs is running dry. Estimation of the number of deaths caused by antibiotic resistant bacteria within the next decades is worrisome. In this context, the interest for using bacteriophages, viruses that recognize, infect and lyse specifically bacteria, is growing supported by experimental data and case reports.
During this talk, I’ll highlight the challenges for researchers and clinicians to perform translational research for improving patient’s access to phage therapy. More specifically, I will show how the use of animal models helped us deciphering the parameters involved in the efficacy of treatments in terms of doses and route of administration of bacteriophages (pharmacometry), as well as host response (immune cells) and phage resistance (molecular mechanisms).

 

Afin d'assister à cette conférence vous pourrez vous connecter sur le lien zoom suivant :

Sujet : Lundi de Saint Antoine

12 septembre 2022 12:30 PM Paris

Participer à la réunion Zoom

https://us02web.zoom.us/j/82241635015?pwd=dFd3L0l3MmdOaUpUdmhZMEY5UEpsZz09

ID de réunion : 822 4163 5015

Code secret : 920449

Hôpital St-Antoine

Bâtiment Kourilsky
34 rue Crozatier
75012 PARIS

Sorbonne Université
27 rue Chaligny
75012 PARIS

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