• Mardi, 20 Octobre 2020 - 13:05:20

Dernières publications

Publication de diverses études scientifiques

01 - Février - 2019
Diabetes. 2019;68(2):305-17 Widely used for their anti-inflammatory and immunosuppressive properties, glucocorticoids are nonetheless responsible for the development of diabetes and...

11 - Janvier - 2019
Arthritis Res Ther. 2019;21(1):18 Background : Accumulation of advanced glycation end-products (AGEs) is involved in age-related osteoarthritis (OA). Glyoxalase (Glo)-1 is the main enzyme...

10 - Janvier - 2019
Toxicol Sci. 2019;168(2):474-85 Drug-induced cholestasis is mostly intrahepatic and characterized by alterations of bile canaliculi dynamics and morphology as well as accumulation of bile...

01 - Janvier - 2019
Diabetes. 2019;68(1):95-108 Both type 1 and type 2 diabetes are characterized by deficient insulin secretion and decreased beta-cell mass. Thus, regenerative strategies to increase...

01 - Janvier - 2019
J Steroid Biochem Mol Biol. 2019;185:150-62 Insulin resistance is frequently present in patients with glucocorticoid (GC) excess (Cushing's syndrome) or treated with high doses of GCs....

22 - Décembre - 2018
Joint Bone Spine. 2018 Metabolic syndrome-associated osteoarthritis (Met-OA) is a clinical phenotype defined by the role of obesity and metabolic syndrome as risk factors and by chronic...

19 - Décembre - 2018
Aliment Pharmacol Ther. 2019;49(3):308-20 Background : No blood test has been shown to be effective in the prediction of primary liver cancer in patients without cirrhosis. AIM: To...

01 - Décembre - 2018
Hepatol Commun. 2018;2(12):1533-49 The most typical expression of cystic fibrosis (CF)-related liver disease is a cholangiopathy that can progress to cirrhosis. We aimed to determine the...

06 - Novembre - 2018
Cell Metab. 2018;28(5):737-49 e4 The extent to which microbiota alterations define or influence the outcome of metabolic diseases is still unclear, but the byproducts of microbiota...

01 - Novembre - 2018
Aliment Pharmacol Ther. 2018;48(9):961-74 Background : Intestinal microbiota plays an important role in bile acid homeostasis. Aim : To study the structure of the intestinal microbiota...

22 - Octobre - 2018
EMBO Rep. 2018;19(11) Primary cilia (PC) are antenna-like organelles that protrude from most mammalian cells. They are essential for the regulation of several signaling pathways such as...

08 - Octobre - 2018
Biophys Acta Mol Basis Dis. 2018;1864(12):3688-96 Portal myofibroblasts (PMF) form a sub-population of highly proliferative and proangiogenic liver myofibroblasts that derive from portal...

01 - Octobre - 2018
Gut. 2018;67(10):1836-44 Objective : In association with innate and adaptive immunity, the microbiota controls the colonisation resistance against intestinal pathogens. Caspase recruitment...

12 - Septembre - 2018
Nat Rev Rheumatol. 2018;14(11):674-81 The prevalence of osteoarthritis (OA) is rising for reasons that are not fully understood. In this Opinion article, we review the possibility that OA...

11 - Septembre - 2018
J Lipid Res. 2018;59(11):2202-13 Bile acid (BA) secretion and circulation in chronic pancreatitis (CP) patients with exocrine pancreatic insufficiency (EPI) were investigated by...

29 - Août - 2018
PLoS One. 2018;13(8):e0202587 Background and Aims : N-acyl homoserine lactones (AHLs), which are autoinducer quorum-sensing molecules involved in the bacterial communication network, also...

02 - Août - 2018
Int J Cancer. 2018;143(10):2458-69 Insulin and insulin-like growth factor (IGF)-1 signaling in the thyroid are thought to be permissive for the coordinated regulation by thyroid-stimulating...

01 - Août - 2018
Best Pract Res Clin Endocrinol Metab. 2018;32(4):523-34 Fetal growth restriction (FGR) can result from multiple causes, such as genetic, epigenetic, environment, hormonal regulation, or...

25 - Juillet - 2018
J Clin Lipidol. 2018;12(6):1420-35 Background : Multiple symmetric lipomatosis (MSL) is characterized by upper-body lipomatous masses frequently associated with metabolic and neurological...

18 - Juillet - 2018
Nat Commun. 2018;9(1):2802 Dietary lipids favor the growth of the pathobiont Bilophila wadsworthia, but the relevance of this expansion in metabolic syndrome pathogenesis is poorly...

09 - Juillet - 2018
J Pathol. 2018;246(2):217-30 Obesity and its metabolic complications are characterized by subclinical systemic and tissue inflammation. In rodent models of obesity, inflammation and...

18 - Juin - 2018
Dev Cell. 2018;45(6):712-25 e6 Cancer cachexia is characterized by extreme skeletal muscle loss that results in high morbidity and mortality. The incidence of cachexia varies among tumor...

13 - Juin - 2018
Cell Host Microbe. 2018;23(6):716-24 The gut microbiota is a crucial actor in human physiology. Many of these effects are mediated by metabolites that are either produced by the microbes or...

07 - Juin - 2018
N Engl J Med. 2018;378(23):2171-81 Background : Patients with primary biliary cholangitis who have an inadequate response to therapy with ursodeoxycholic acid are at high risk for disease...

29 - Mai - 2018
Stem Cells. 2018;36(9):1421-9 Heterozygous PAX6 gene mutations leading to haploinsufficiency are the main cause of congenital aniridia, a rare and progressive panocular disease...

15 - Mai - 2018
Mol Biol Cell. 2018;29(10):1178-89 The vertebrate hedgehog pathway is organized in primary cilia, and hedgehog components relocate into or out of cilia during signaling. Defects in...

03 - Mai - 2018
Clin Cancer Res. 2018;24(17):4282-96 Purpose : Cholangiocarcinoma (CCA) is a desmoplastic tumor of the biliary tree in which epidermal growth factor receptor (EGFR) is overexpressed and...

19 - Avril - 2018
Physiol Rep. 2018;6(8):e13678 The RORalpha-deficient staggerer (sg/sg) mouse is lean and resistant to diet-induced obesity. Its thermogenic activity was shown to be increased not only in...

15 - Avril - 2018
Hum Mol Genet. 2018;27(8):1447-59 The p.R482W hotspot mutation in A-type nuclear lamins causes familial partial lipodystrophy of Dunnigan-type (FPLD2), a lipodystrophic syndrome complicated...

11 - Avril - 2018
J Clin Endocrinol Metab. 2018;103(7):2436-46 Context : Silver-Russell syndrome (SRS) (mainly secondary to 11p15 molecular disruption) and Temple syndrome (TS) (secondary to 14q32.2...

Centre de Recherche
Saint-Antoine
UMR_S 938

Hôpital St-Antoine

Contact

Tél : +(33) 1 49 28 46 00